A Comparison of the Behavior of 64Cu-Acetate and 64Cu-ATSM In Vitro and In Vivo

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UNLABELLED We have evaluated Cu-diacetyl-bis(N4-methylthiosemicarbazone) (Cu-ATSM), an effective marker for the delineation of hypoxic but viable tissue, in vitro in the EMT6 carcinoma cell line under varying degrees of hypoxia and compared it with the flow tracer 64Cu-pyruvaldehyde-bis(N4-methylthiosemicarbazone) (Cu-PTSM) and the hypoxic tracer 18F-fluoromisonidazole (MISO). We have also comp...

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ژورنال

عنوان ژورنال: Journal of Nuclear Medicine

سال: 2013

ISSN: 0161-5505,2159-662X

DOI: 10.2967/jnumed.113.119917